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. 2015 Jun 12;59(7):3808–3815. doi: 10.1128/AAC.00421-15

FIG 1.

FIG 1

Antibacterial activity of tobramycin (open circles), cathelicidin LL-37 peptide (filled squares), ceragenin CSA-13 (open triangles), CSA-90 (filled circles), CSA-131 (filled triangles), and D2S (open squares) against P. aeruginosa LESB58 (A), P. aeruginosa (PA) Xen5 (B), and five different clinical isolates of P. aeruginosa originating from cystic fibrosis sputum shown as average values (C). All results were compared to control. LESB58 bacterial growth (D through F) and bactericidal activity of LL-37 peptide (filled squares), CSA-13 (open triangles), and CSA-131 (filled triangles) in the presence of bacteriophage Pf1 (D), F-actin (E), and DNA (F). Open inverted triangles represent control group (LESB58 growth in the presence of Pf1, F-actin, or DNA [D, E, and F, respectively]). Error bars represent standard deviations from three to six measurements. * and ^ indicate statistical significance (P < 0.05) compared to control (logCFU with 0 μg/ml of tested antibacterial agent for A through C or LESB58 growth in the presence of Pf1, F-actin, or DNA for D through F) or samples treated with LL-37 peptide, respectively.