TABLE 2.
Antimicrobial susceptibility profiles of extended-spectrum-cephalosporin-resistant V. parahaemolyticus strains (V4, V43, 2010V36, and 2011V1) and the corresponding transconjugants
| Strain | β-Lactamase gene | MIC (mg/liter) ofa: |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMP (32) | CTX (4) | CRO (4) | CAZ (16) | CEP (16) | TET (16) | GEN (16) | NAL (32) | CIP (4) | CHL (32) | KAN (64) | TRI (16) | ||
| J53b | 1 | ≤0.125 | ≤0.125 | ≤0.125 | ≤0.125 | 2 | 1 | 2 | ≤0.125 | 2 | 0.25 | ≤0.125 | |
| V4 | blaCMY-2 | 128 | 8 | 32 | 8 | 0.5 | 32 | 1 | 0.5 | ≤0.125 | 2 | 8 | 16 |
| V4-J53 | blaCMY-2 | >128 | 16 | 64 | 64 | 0.5 | 64 | 1 | 2 | ≤0.125 | 64 | 1 | >64 |
| V43 | blaPER-1 | >128 | >128 | >128 | >128 | 32 | 32 | 8 | 1 | ≤0.125 | 2 | 8 | 32 |
| V43-J53 | blaPER-1 | 128 | 128 | 128 | >128 | 16 | 64 | 8 | 2 | ≤0.125 | 32 | 0.5 | >64 |
| 2010V36 | blaPER-1 | >128 | >128 | >128 | >128 | 32 | 1 | 1 | 0.25 | ≤0.125 | 0.25 | 2 | 16 |
| 2010V36-J53 | blaPER-1 | >128 | >128 | >128 | >128 | 16 | 2 | 1 | 2 | ≤0.125 | 2 | 2 | >64 |
| 2011V1 | blaPER-1 | >128 | >128 | >128 | >128 | 16 | 1 | 4 | 0.5 | ≤0.125 | 16 | 64 | >64 |
| 2011V1-J53 | blaPER-1 | >128 | >128 | >128 | >128 | 32 | 2 | 4 | 4 | ≤0.125 | 16 | 64 | >64 |
a
Numbers in parentheses are the breakpoint for each agent. AMP, ampicillin; CTX, cefotaxime; CRO, ceftriaxone; CAZ, ceftazidime; CEP, cefepime; TET, tetracycline; GEN, gentamicin; NAL, nalidixic acid; CIP, ciprofloxacin; CHL, chloramphenicol; KAN, kanamycin; TRI, trimethoprim.
b
J53, E. coli recipient.