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Arylomycin A-C16 MIC change for Y. pestis RS 058 (black bars), which contains pBAD-EcLepB, and a mock-transfected control Y. pestis containing pBAD-empty (white bars) as a function of increasing l-arabinose. The MICs for RS 058 and the mock-transfected Y. pestis in the absence of l-arabinose were 8 and 2 μg/ml, respectively. For RS 058, the arylomycin A-C16 MICs at 0.5 to 2% l-arabinose were >64 μg/ml. To calculate the fold change, the MICs were taken to be 128 μg/ml.
