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. 2015 Jun 12;59(7):4249–4259. doi: 10.1128/AAC.04942-14

TABLE 2.

Pharmacokinetic measures as means and corresponding ranges for C_max, T_max, t_1/2, and AUC measurements of sulfadoxine and pyrimethamine

Drug	Mean (range)^a
Drug	C_max	T_max (h)	t_1/2 (days)	AUC_0–96	AUC_0–∞
Sulfadoxine	135 mg/liter (110–176)	10.8 (4–36)	7.3 (4.9–13.2)	10,044 (8,422–12,244)	31,848 (21,705–49,365)
Pyrimethamine	714 μg/liter (610–832)	3.8 (2–8)	3.9 (2.1–6.5)	42,701 (33,922–53,872)	87,786 (51,612–140,201)

^a

AUC_0–96 and AUC_0–∞, AUC from 0 to 96 h and from 0 h to infinity, respectively.