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Inhibitory steady-state kinetic parameters for SHV-1 and the SHV-1 S130G variant with AVI
| Parameter | SHV-1 | SHV-1 S130G |
|---|---|---|
| NCF Km (μM) | 12.5 ± 2.5 | 3,107 ± 2393 |
| NCF kcat/Km (μM−1 s−1) | 15.3 | 0.02 |
| AVI k2/K (M−1 s−1) | 60,300 | 1.3 |
| AVI Ki app (μM) | 0.022 ± 0.002 | 10,274 ± 1,000 |
| AVI 24-h partition ratio | 1 | 1 |
