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. 2015 May 6;130(1):63–75. doi: 10.1007/s00401-015-1429-9

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Immunohistochemistry reveals the distribution of dipeptide repeat protein containing inclusions consisting of species derived from sense and antisense repeat RNAs in two neuronal populations. Representative images showing that poly-GA and poly-GR containing inclusions are more numerous in cerebellar granule neurons, whereas poly-PA and poly-PR containing inclusions are more numerous in motor neurons. Staining was carried out individually for each protein (a) and then poly-GA and poly-PA were examined by dual staining (b). Inclusions are highlighted by arrowheads. Scale bar 3 µm