Skip to main content
. 2015 Jun 16;5:11373. doi: 10.1038/srep11373

Figure 3. TGF-β1-Smad2 pathway was involved in bystander micronucleus formation in unirradiated WS1 cells co-cultured with α-irradiated HaCaT cells.

Figure 3

Panel a, the effect of SB431542 on the bystander micronucleus formation in unirradiated WS1 cells. * P <0.05 compared with the WS1 cells co-cultured with sham irradiated HaCaT cells. Panel b, the phosphorylation of Smad2 in HaCaT cells at various times after α- irradiation. Panel c, the effect of SB431542 on the phosphorylation of Smad2 in HaCaT cells 1 h after α-irradiation. Panel d, In contrast with α-irradiation, X-rays did not cause phosphorylation of Smad2 in HaCaT cells 1 h after radiation up to 10 Gy.