Table 2.

Relation Between Independent Variables and Dose-Corrected Plasma Clozapine Concentration^a,b

				95% Confidence Interval
Independent Variablec	β	Standard Error	P ≤	Lower	Upper
CYP1A2 rs762551 AA genotype	−2.0	0.75	.008	−3.54	−0.55
Currently smoking	−1.8	0.76	.03	−3.31	−0.28
MDR1 rs2032582 GG genotype	−1.7	0.85	.05	−3.45	−0.05
Constant	11.4	1.69	.001	8.02	14.72

^aMultiple regression analysis (stepwise forward).

^bR² = 0.16.

^crs762551 AA genotype (no = 0, yes = 1), smoking status (no = 0, yes = 1), rs2032582 GG genotype (no = 0, yes = 1).

Abbreviations: CYP=cytochrome P450, MDRI=multidrug resistance protein 1.