Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model cartoon of the protection after infection with an MHC-downregulating virus. An iNKR becomes licensed if it binds at least one MHC molecule in the host. In this example, the iNKR is licensed by binding the MHC-X molecule in that host. The virus downregulates the expression of all MHC-X molecules. The infection can be cleared with a probability pcl = 0.6 if and only if the licensed iNKR fails to bind all MHC-Y molecules in that host (see Materials and Methods).
