Table 1.

Comparison of cytokine levels in maternal blood (a) and amniotic fluid (b) at trimester 2 (10) and trimester 3.

	Maternal blood
	14–16 weeks N = 33	37.6–40.3 weeks N = 24
	Median (range) (pg ml−1) N = 33	Median (range) (pg ml−1) N = 24
IFN-γ	113 (34–431)	41 (< 11 – 772)
IL-1β	7 (2–360)	< 2.4 (< 2.4 – 21)
IL-6	22 (6–2116)	59 (10 – 74)
IL-8	17 (3–98)	90 (36 – 3289)
TNF-α	53 (4–392)	16 (< 5.4 – 32)
IL-10	3 (<1–1206)	11 (< 1.8 – 160)
IL-1ra	284 (21–8620)	90 (< 4 – 230)
	Amniotic fluid
	14–16 weeks N = 100	37.6 – 40.3 weeks N = 24
	Median (range) (pg ml−1) (n = 100)	Median (range) (pg ml−1) (n = 24)
IFN-γ	22 (5–132)	1804 (15 – 14, 417)
IL-1β	1.5 (<1–5)	45 (< 2.4 – 69)
IL-6	230 (28–2621)	2118 (646 – 12, 928)
IL-8	188 (29–1648)	2066 (578 – 7082)
TNF-α	18 (<1–153)	538 (24 – 3176)
IL-10	3 (<1–9)	73 (< 1.8 – 303)
IL-1ra	758 (85–3833)	2357 (330 – 6295)