Table 1.

Isoform-specific allosteric activation of cAMP-dependent protein kinase

Complex	K a	Hill coefficient
RIα2:C2	101 nM	1.7
RIβ2:C2	29 nM	1.4
RIIα2:C2	137 nM	1.5
RIIβ2:C2	584 nM	1.8
RIIβ(108–402):C	65 nM	0.82
RIIβ(1–280)2:C2	60 nM	1.2
RIIβ(R230K)2:C2	12.9 μM	0.99
RIIβ(R359K)2:C2	490 nM	0.62
RIIα(90–400):C	40 nM	0.81

The values of the K _a (activation coefficient) and Hill coefficient are from Zawadzki and Taylor (2004), Ilouz et al. (2012) and Zhang et al. (2012)