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. 2015 Apr 11;262(6):1447–1454. doi: 10.1007/s00415-015-7731-6

Table 3.

This table summarises the Kaplan–Meier estimated median survival time for the patients in the Irish test cohorts and the Italian cohort classified by ALSFRS-R slope only

ALSFRS-R slope (points/month) Irish test set Italian cohort
N Median survival 95 % CI N Median survival 95 % CI
<0.25 14 79.0 66.4–91.6 18 78.0 28.3–127.7
0.25–0.45 21 45.0 31.6–58.3 31 43.0 23.5–63.5
0.50–0.99 36 36.0 27.3–36.7 40 35.0 27.3–42.7
≥1.0 16 16.0 27.3–36.7 33 28.0 4.1–51.5
Log rank p value <0.0001 0.004