Table 2.
Resistance markers detected by the mPCR device (according to the manufacturer)
| Resistance marker | Resistance against | Relevant pathogen groupa |
|---|---|---|
| mecA | Oxacillin, Methicillin | Staphylococcus species |
| msrA | Macrolides | Staphylococcus species |
| mefA/E | Macrolides | Streptococcus species |
| ermA | Macrolides / Lincosamides | Staphylococcus species |
| ermB | Macrolides / Lincosamides | Streptococcus species |
| ermC | Macrolide / Lincosamides | Staphylococcus species |
| tem | Penicillins, 3rd Gen. Cephalosporins | Enterobacteriaceae, Non-fermenting bacteria, Haemophilus influenzae |
| shv | Penicillins, 3rd Gen. Cephalosporin | Enterobacteriaceae, Non-fermenting bacteria |
| ctx-M | Penicillins, 3rd Gen. Cephalosporins | Enterobacteriaceae, Non-fermenting bacteria |
| dha | 3rd Gen. Cephalosporins | Enterobacteriaceae |
| ebc | 3rd Gen. Cephalosporins | Enterobacteriaceae |
| oxa51 like | Carbapenems | Acinetobacter baumanii |
| kpc | Carbapenems | Enterobacteriaceae, Non-fermenting bacteria |
| int1 | Multidrug resistance | Enterobacteriaceae, Non-fermenting bacteria |
| sul1 | Multidrug resistance, Sulfonamides | Enterobacteriaceae, Non-fermenting bacteria |
| gyrA83 | Fluoroquinolones | Escherichia coli, Pseudomonas aeruginosa |
| gyrA87 | Fluoroquinolones | Escherichia coli, Pseudomonas aeruginosa |
| parC | Fluoroquinolones | Pseudomonas aeruginosa |
a pathogen/group of pathogens in which the resistance marker gene is found (according to the manufacturer)