Fig. 3.

Estimated proportions from the 3-component Gaussian mixture model of the cell-free fragment lengths separated by chromosome. For both samples I1_M_plasma and G1_M_plasma, these estimates approximate the proportion of mono-, di- and tri-nucleosome lengths in each chromosome. All other mixture model parameters are reported in Additional file 4. The solid lines depict the average value in each component while the dashed lines demarcate +/- 3 standard deviations from the mean