Table 2.
Areas of significant brain activation: regions of interest and corresponding Brodmann area, function, t-score and Talairach coordinates of the voxel with the peak t-score, size. Areas with increased BOLD-signal after Bonferroni correction (p<.001) are highlighted.
| Anatomical Location | Functional Location | BA | Talairach Coordinates (x, y, z) | Size (mm3) | Max t-Score |
|---|---|---|---|---|---|
| Premotor cortex, Supplementary motor area (I) | Motor | 6 | −11, −27, 68 | 10138 | 8.82* |
| Primary motor cortex (I) | Motor | 4 | −10, −27, 68 | 5991 | 8.75* |
| Precuneus (I) | Somatosensory association | 7 | 2, −83, 33 | 5464 | 8.25* |
| Occipital (C) | Visual | 18,19 | 3, −83, 33 | 7986 | 8.21* |
| Posterior cingulate (I) | Limbic | 30 | −4, −64, 14 | 3506 | 8.02* |
| Precuneus (C) | Somatosensory association | 7 | 3, −67, 51 | 3679 | 7.76* |
| Occipital (I) | Visual | 17,19 | −14, −81, 12 | 10164 | 7.65* |
| Primary Somatosensory cortex (I) | Somatosensory | 3 | −11, −40, 63 | 4859 | 7.40* |
| Cingulate gyrus (I) | Limbic | −4, −25, 52 | 3850 | 6.79* | |
| Premotor cortex (C) | Motor | 6 | 34, 6, 46 | 2274 | 6.67* |
| Cerebellum (C) | Motor | 3, −52, −5 | 903 | 6.46* | |
| Pedunculopontine nucleus (I) | Motor | −11, −28, −9 | 1617 | 6.11* | |
| Parahippocampal gyrus (I) | Limbic | 28,35,36 | −16, −12, −25 | 888 | 6.07 |
| Caudate (I) | Motor | −25, −12, 35 | 121 | 5.79 | |
| Supramarginal gyrus (C) | Visuospatial | 40 | 35, −47, 38 | 1383 | 5.77 |
| Insula (C) | Limbic | 13 | 33, −18, 26 | 399 | 5.39 |
| Thalamus (I) | Motor | −10, −10, 9 | 528 | 5.34 | |
| Inferior frontal gyrus (I) | Language | 45,47 | −56, 8, −1 | 990 | 5.25 |
| Superior parietal lobule (I) | Somatosensory association | 7 | −32, −60, 53 | 349 | 5.24 |
| Posterior cingulate (C) | Limbic | 29 | 3, −51, 12 | 709 | 5.23 |
| Middle frontal gyrus (I) | Executive | 10 | −34, 37, 16 | 1021 | 5.03 |
| Superior parietal lobule (C) | Somatosensory association | 7 | 21, −59, 40 | 640 | 5.03 |
| Cerebellum (I) | Motor | −21, −32, −23 | 80 | 4.90 | |
| Anterior cingulate (I) | Limbic | 32 | −8, 37, 19 | 355 | 4.89 |
| Parahippocampal gyrus (C) | Limbic | 36 | 24, −44, −17/41, −36, −6 | 80/40 | 4.87/−4.50 |
| Inferior temporal gyrus (I) | Language, Visual | 20,37 | −64, −42, −23 | 574 | 4.86 |
| Angular gyrus (I) | Language | 39 | −31, −64, 23 | 145 | 4.57 |
| Middle temporal gyrus (I) | Auditory, Language | 21 | −45, −5, −16 | 73 | 4.55 |
| Cingulate gyrus (C) | Limbic | 31 | 12, −41, 34 | 111 | 4.54 |
| Pons (C) | 6, −34, −21 | 24 | 4.50 | ||
| Postcentral gyrus (C) | Language, | 3,43 | 51, −17, 22 | 53 | 4.44 |
| Angular gyrus (C) | Visuospatial | 39 | 36, −45, 7 | 42 | 4.40 |
| Primary motor cortex (C) | Motor | 4 | 17, −23, 50 | 25 | 4.26 |
| Middle temporal gyrus (C) | Auditory | 22 | 49, −44, −1 | 25 | 4.22 |
| Supramarginal gyrus (I) | Language | 40 | −36, −54, 28/−56, −44, 20 | 29/110 | 4.20/−5.22 |
| Orbitofrontal (C) | Associative | 11 | 22, 41, −15 | 5 | 4.20 |
| Inferior frontal gyrus (C) | Language | 44 | 50, 0, 12 | 13 | 4.18 |
| Superior temporal gyrus (C) | Cognition, Limbic | 38 | 48, 13, −2 | 4 | 4.10 |
| Dorsolateral prefrontal cortex (I) | Executive | 46 | −40, 45, 8 | 4 | 4.09 |
| Fusiform gyrus(C) | Visual | 37 | 34, −58, −5 | 8 | 4.08 |
| Superior temporal gyrus (I) | Language | 22 | −43, −37, −1 | 46 | −4.53 |
Abbreviations: BA: Brodmann Area; C: Contralateral; I: Ipsilateral
*
Areas showing with Bonferroni correction P < .001