. Author manuscript; available in PMC: 2016 May 1.

Published in final edited form as: Transplantation. 2015 May;99(5):1003–1008. doi: 10.1097/TP.0000000000000454

Table 3.

Overall Safety Events in FAVORIT Participants

	Participant		Visit ⁺
	N	%	N	%

Drug Interaction
CNI and Statin	2524/4110	61.4	7898/16327	47.4
AZA and ACEI	378/4110	9.2	1036/16327	6.3

Metformin Use Stratified by GFR tertile	Participant^*		Visit^**
Low tertile GFR	45/1325	3.4	104/5081	2.0
Middle tertile GFR	54/1322	4.1	124/5330	2.5
High tertile GFR	65/1359	4.7	140/5496	2.6

Sulfonyluree use Stratified by GFR tertile	Participant^***		Visit^****
Low tertile GFR	171/1325	12.9	388/5081	7.6
Middle tertile GFR	182/1322	13.8	429/5337	7.9
High tertile GFR	180/1369	13.1	425/5496	7.5

⁺

Rates computed using proc logistic scale=Williams.

CNI=calcineurin inhibitor, AZA=azathioprine, ACEI=angiotensin-converting enzyme inhibitor, GFR=estimated glomerular filtration rate

p value = 0.08,

^**

p value = 0.09,

^***

p value = 0.80,

^****

p value = 0.72