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. Author manuscript; available in PMC: 2015 Jun 16.
Published in final edited form as: Curr Pharm Biotechnol. 2011 Sep;12(9):1455–1462. doi: 10.2174/138920111798281027

Figure 6. Pretreatment with simvastatin attenuates expression of the genes for soluble inflammatory mediators following challenge with S. aureus.

Figure 6

Expression of the target sequences (TNF-α, IL-6, IL-1β, RANTES, MIP2 and IL-10) was assessed by qRT-PCR and normalized to β-actin or to 18S ribosomal RNA. Data are expressed as fold change relative to unchallenged mice pretreated with normal saline. *p≤0.05. U=Uninfected mice, I=Infected mice. n= 5 mice per group.