Fig. 4.
Individual changes in plasma exposure (AUC0–24 h) and maximum concentrations (C max) for tamoxifen (a, b) and endoxifen (c, d) after tamoxifen administration at three different times; morning (8 a.m.), afternoon (1 p.m.), and evening (8 p.m.) in 12 women. For two patients, AUC0–24 h data (1 p.m.) were lacking