Table 3. The characteristics of included studies.
First author | Year | Country | Ethnicity | Genotyping method | Histological type | Case/Control(Never smoked) | Case/Control(Male) | Case/Control(Total) | OR(95%CI) | HWE P |
---|---|---|---|---|---|---|---|---|---|---|
Schwartz-W | 2009 | USA | Caucasian | Taqman | NSCLC | 111/451 | — | 630/835 | 1.25(1.06-1.46) a | 0.09 |
Schwartz-AA | 2009 | USA | African-American | Taqman | NSCLC | 41/196 | — | 402/435 | 1.41(1.10-1.81) a | 0.40 |
Truong | 2010 | France | Asian | Taqman | Lung Cancer | 674/1270 | 838/902 | 1694/2126 | 1.03(0.93-1.14) a | 0.10 |
&Illumina | ||||||||||
Hsiung | 2010 | China | Asian | Taqman | Lung Cancer | 2563/2541 | 0/0 | 2563/2541 | 1.15(0.97-1.36) b | 0.22 |
Ito | 2012 | Japan | Asian | Taqman | Lung Cancer | 177/290 | 531/531 | 716/716 | 1.15(0.98-1.35) a | 0.29 |
Current Study | 2014 | China | Asian | Taqman | Lung Cancer | 279/599 | 419/746 | 611/1062 | 1.29(1.11, 1.49) a | 0.92 |
Abbreviations: NSCLC, non-small cell lung cancer; OR, Odds ratio; 95%CI, 95% confidence interval; HWE, Hardy-Weinberg equilibrium.
a OR was calculated under additive model.
b OR was calculated under dominant model.