Table 4. Meta-analysis of the rs931794 in association with lung cancer risk.
| Category | Genetic model | OR(95%CI) | P | I 2 | tau | P for heterogeneity |
|---|---|---|---|---|---|---|
| Overall | AG/AA | 1.141(1.061-1.227) | <0.001 | 0.0 | <0.0001 | 0.617 |
| (n = 6) | GG/AA | 1.263(1.007-1.583) | 0.043 | 73.6 | 0.234 | 0.002 |
| Dominant model | 1.143(1.068-1.224) | <0.001 | 35.4 | 0.066 | 0.172 | |
| Recessive model | 1.166(0.947-1.437) | 0.148 | 72.8 | 0.214 | 0.002 | |
| G/A | 1.144(1.038-1.262) | 0.007 | 69.7 | 0.099 | 0.006 | |
| Additive model | 1.139(1.036-1.252) | 0.007 | 68.1 | 0.095 | 0.008 | |
| Ethnicity / Histological type | ||||||
| Asian (n = 4) / | AG/AA | 1.114(1.029-1.206) | 0.007 | 0.0 | <0.0001 | 0.853 |
| Lung cancer | GG/AA | 1.209(0.911-1.603) | 0.189 | 80.9 | 0.256 | 0.001 |
| (n = 4) | Dominant model | 1.111(1.031-1.197) | 0.006 | 21.2 | 0.041 | 0.283 |
| Recessive model | 1.134(0.868-1.481) | 0.356 | 81.4 | 0.243 | 0.001 | |
| G/A | 1.107(0.989-1.239) | 0.077 | 73.5 | 0.097 | 0.010 | |
| Additive model | 1.103(0.989-1.230) | 0.079 | 72.3 | 0.093 | 0.013 | |
| Genotyping method | ||||||
| Taqman | AG/AA | 1.146(1.054-1.246) | 0.001 | 0.0 | <0.0001 | 0.478 |
| (n = 5) | GG/AA | 1.336(0.997-1.790) | 0.052 | 77.6 | 0.285 | 0.001 |
| Dominant model | 1.156(1.068-1.250) | <0.001 | 46.2 | 0.090 | 0.114 | |
| Recessive model | 1.228(0.939-1.607) | 0.134 | 76.8 | 0.260 | 0.002 | |
| G/A | 1.176(1.037-1.334) | 0.012 | 74.3 | 0.121 | 0.004 | |
| Additive model | 1.169(1.035-1.320) | 0.012 | 72.9 | 0.116 | 0.005 | |
Abbreviations: OR, Odds ratio; 95%CI, 95% confidence interval.