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. 2015 Jun 16;10(6):e0129724. doi: 10.1371/journal.pone.0129724

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© 2015 Aarstad et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — HNSCC versus control patients (upper panel) and HNSCC patients adjusted by whether HPV infected tumor (lower panel). IL-6 in vitro secretion of purified monocytes determined by ELISA analyses following 24-hour LPS stimulation. Cytokine levels with background subtracted dichotomized by median value to low (continuous line) or high (hatched line) response. Cohort (upper panel): 55 HNSCC and 18 control patients. Cohort (lower panel): 48 HPV-negative and 7 HPV-positive HNSCC patients. Statistics by Kaplan-Meier analyses (Log rank test).