Table 1.

Live attenuated Salmonella vaccines

Serovar	Vaccine	Parent	Genotype	Developer	Stage	References
Typhi	CVD 906	ISP1820	ΔaroC ΔaroD	CVD	Phase 1	[75]
	CVD 908	Ty2	ΔaroC ΔaroD	CVD	Phase 1	[19, 20, 72–74]
	CVD 906-htrA	ISP1820	ΔaroC ΔaroD ΔhtrA	CVD	Phase 1	[20]
	CVD 908-htrA	Ty2	ΔaroC ΔaroD ΔhtrA	CVD	Phase 1 and 2	[20]
	CVD 909	Ty2	ΔaroC ΔaroD Ptac-tviA	CVD	Phase 1	[78]
	Typhella (M01ZH09)	Ty2	ΔaroC ΔssaV	Prokarium	Phase 1 and 2	[79–81, 107–109]
	χ3927	Ty2	Δcya Δcrp	Curtiss, R. 3rd	Phase 1	[19]
	Ty800	Ty2	ΔphoPQ	Celldex Therapeutics	Phase 1 and 2	[82]
Paratyphi A	CVD 1902	ATCC 9150	ΔguaBA ΔclpX	CVD	Phase 1	ClinicalTrials.gov: NCT01129453
	MGN10028	MGN9772	ΔphoPQ	Celldex Therapeutics	Pre-clinical	[83]
Paratyphi B	CVD 2005	CMF 6999	ΔguaBA ΔclpX	CVD	Pre-clinical	Higginson E., unpublished data
Typhimurium	CVD 1921	I77	ΔguaBA ΔclpP	CVD	Pre-clinical	[49]
	CVD 1931	D65	ΔguaBA ΔclpX	CVD	Pre-clinical	Tennant, S.M., unpublished data
Enteritidis	CVD 1941	R11	ΔguaBA ΔclpP	CVD	Pre-clinical	[49]
	CVD 1944	R11	ΔguaBA ΔclpX	CVD	Pre-clinical	Tennant, S.M., unpublished data
Paratyphi C (C1)	TBD	TBD	TBD	CVD	Pre-clinical	Fuche, F., unpublished data
Newport (C2)	TBD	TBD	TBD	CVD	Pre-clinical	Fuche, F., unpublished data

TBD, To be determined