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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Dev Biol. 2015 Apr 24;403(1):30–42. doi: 10.1016/j.ydbio.2015.03.017

Figure 4. Macrophage engulfment of endothelial cell membrane particles begins during embryogenesis.

Figure 4

At E12.5, the vasculature has begun to form within the PM, but the resident macrophages have yet to acquire Cherry+ membrane particles (A-C). By E14.5, the PM vasculature is established (D) and a subset of macrophages contains membrane particles (arrowhead in E-F). All of the PM macrophages are positive for membrane particles at E18.5 (G and arrowheads in H-I). N>5.