Skip to main content
. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Alcohol. 2015 Apr 28;49(5):499–506. doi: 10.1016/j.alcohol.2015.03.004

Table 1.

Blood ethanol concentrations (mg/dL) following ethanol (1 g/kg; 10 mL/kg of 13% ethanol in water) in conscious male Sprague-Dawley rats

Time (min)
Group 30 60
Ethanol + Saline 42 ± 6.0 42 ± 9.7
Ethanol + NMDA 26 ± 1.3* 24 ± 6
Ethanol + NMDA infusion 36 ± 2.6 29 ± 1.7
Saline + Ethanol (1 g/kg) 39 ± 8.1 27 ± 2.9
AP-5 + Ethanol (1 g/kg) 28 ± 6.7 21 ± 5.4
Saline + Ethanol (1.5 g/kg) 83 ± 5.1
AP-5 + Ethanol (1.5 g/kg) 91 ± 5.3

Values are means ± standard error of the mean of 4–6 observations. AP-5, DL-2-Amino-5-phosphonopentanoic acid; NMDA, N-Methyl-D-Aspartate

*

p < 0.05 versus ethanol + saline treatment group (Student’s t test)