Table 3. IgG and IgG2 directed against recombinant AM854 and AM936 following immunization with recombinant proteins, purified outer membranes or adjuvant alone.
AM854 | AM936 | |||||
---|---|---|---|---|---|---|
Immunogen | Animal No. | DRB3 haplotype | IgG | IgG2 | IgG | IgG2 |
Recombinant Proteins | 93 | *0101/*0101 | 1000 | 300 | 3000 | 1000 |
107 | *0101/*1401 | 300 | 300 | 1000 | 1000 | |
126 | *0101/*1101 | 300 | 100 | 3000 | 1000 | |
140 | *0101/*1001 | 300 | 100 | 1000 | 1000 | |
146 | *0101/*1501 | 1000 | 300 | 3000 | 1000 | |
Outer membrane proteins | 71 | *0101/*0101 | 300 | 100 | 3000 | 3000 |
92 | *0101/*1501 | 1000 | 300 | 3000 | 1000 | |
100 | *0101/*1001 | 300 | 100 | 3000 | 1000 | |
105 | *0101/*1401 | 100 | <100 | 1000 | 1000 | |
109 | *0101/*1101 | 1000 | 300 | 30000 | 30000 | |
Adjuvant only | 73 | *0101/*1501 | <100 | ND | <100 | ND |
82 | *0101/*1002 | <100 | ND | <100 | ND | |
84 | *0101/*1201 | <100 | ND | <100 | ND | |
130 | *0101/*1101 | <100 | ND | <100 | ND | |
141 | *0101/*1001 | <100 | ND | <100 | ND |