Figure 8. Epicardial and subepicardial fibrosis, right ventricle; 16-week-old mouse (the same case as in Fig. 4a).
Figure 8a. Epicardial and subepicardial fibrosis is present from the base to the middle aspect of the right ventricle (boundaries outlined by arrow heads). HE. Figure 8b. Higher magnification of inset in Figure 8a. A plaque of fibrosis and fibroplasia expands the epicardium and the subepicardium. Low numbers of mainly mononuclear cells are notable at the deeper aspects of the plaque of fibrosis (arrow heads). The underlying myocardium is unremarkable. HE. Figure 8c. Serial section from Figure 8b; collagen deposition is evident within the inner and middle aspect of the lesion (arrow heads). Masson's trichrome stain. LA, left atrium; LV, left ventricle; RA, right atrium; RV, right ventricle.
