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. 2015 May 8;29(6):732–741. doi: 10.1038/eye.2015.58

Table 2. Clinical features associated with response to intravitreal bevacizumab at postoperative 1 month and at last visit.

  Overall At 1 month after the first IVB
At the last visit
    CR group (n=10) NCR group (n=32) P-value CR group (n=25) NCR group (n=17) P-value
Demography
 Age (years) 49.4±11.1 45.4±7.8 50.6±11.7 0.101a 47.5±9.2 52.1 ±13.1 0.298a
 Male/female 26/16 7/3 19/13 0.715b 16/9 10/7 0.757c
 Symptom duration (months) 6.8±10.5 6.7±7.3 6.8±11.4 0.336a 7.0±8.7 6.4±13.0 0.286a
 Spherical equivalent (diopters) -0.45±1.15 -0.28±1.27 -0.52±1.13 0.950a -0.38±1.19 -0.52±1.15 0.823a
 BCVA at baseline (LogMAR) 0.3±0.3 0.1±0.1 0.4±0.4 0.002a 0.3±0.3 0.4±0.4 0.424a
 
FA features
 Classic/DRPE 27/12 5/5 22/7 0.232b 19/4 8/8 0.041b
 From leakage to fovea (μm) 796.6±484.1 886.8±644.2 766.5±429.1 0.747a 752.1±339.4 866.4±660.6 0.936a
 
ICGA features (presence/absence)
 Choroidal hyperpermeability 22/0 5/0 17/0 NA 9/0 13/0 NA
 Choroidal filling delay 16/6 5/0 11/6 0.266b 6/3 10/3 0.655b
 Punctate hyperfluorescence 17/5 3/2 14/3 0.548b 5/4 12/1 0.116b
SD-OCT features (μm)
 SRF GLD 3203.7±1058.8 2587.7±893.2 3396.3±1044.2 0.019a 3232.1±1163.2 3162.1±916.5 0.929a
 SRF height 213.4±101.0 168.8±76.0 227.4±104.8 0.090a 214.7±105.7 211.6±96.8 0.888a
 SRF volume (mm3) 1.0±0.8 0.7±0.5 1.1±0.8 0.090a 1.0±0.8 1.0±0.8 0.798a
 Central macular thickness 429.0±107.1 395.5±73.1 439.4±114.7 0.199a 426.1±102.2 433.2±117.1 0.858a
 Subfoveal choroidal thickness 419.6±135.2 492.9±96.9 389.0±138.7 0.036a 433.3±123.9 402.3±150.9 0.405a

Abbreviations: BCVA, best corrected visual acuity; CR, complete resolution of subretinal fluid; DRPE, diffuse retinal pigment epitheliopathy; FA, fluorescein angiography; GLD, greatest linear diameter; ICGA, indocyanine green angiography; LogMAR, logarithm of minimal angle of resolution; NA, not available; NCR, no complete resolution of subretinal fluid; SD-OCT, spectral domain optical coherence tomography; SRF, subretinal fluid.

a

Mann–Whitney U-test.

b

Fisher's exact test.

c

Pearson's χ2 test.