Table 4. Optimized classification results using BOAS Index (cut-off point BOAS Index = 0.46) for training and test French bulldogs datasets.
| Screening results | |||||
|---|---|---|---|---|---|
| Training dataset (n = 69) | Test dataset (n = 20) | ||||
| BOAS- | BOAS+ | BOAS- | BOAS+ | ||
| Functional Grading a | 0/I (BOAS-) | 28 (TN) | 2 (FP) | 11 (TN) | 0 (FP) |
| II/III (BOAS+) | 1 (FN) | 38 (TP) | 1 (FN) | 8 (TP) | |
| Classification Accuracy | 0.96 (95%CI: 0.91–0.99) | 0.95 (95%CI: 0.85–1.0) | |||
| Sensitivity | 0.97 (95%CI: 0.85–1.0) | 0.89 (95%CI: 0.52–0.98) | |||
| Specificity | 0.93 (95%CI: 0.76–0.99) | 1.0 (95%CI: 0.71–1.0) | |||
| PPV | 0.95 (95%CI: 0.83–0.99) | 1.0 (95%CI: 0.63–1.0) | |||
| NPV | 0.97 (95%CI: 0.82–0.99) | 0.92 (95%CI: 0.61–0.99) | |||
TN = true positive; FP = false positive; FN = false negative; TP = true positive; PPV = positive predictive value; NPV = negative predictive value; BOAS = brachycephalic obstructive airway syndrome.
a Functional grading for BOAS, see Table 1.