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. 2015 Jun 3;2015:758080. doi: 10.1155/2015/758080

Table 2.

Pathological scoring of hepatic tissue after 24 wk on a control or high fat diet.

  C57BL/6J C57BL/6N C3H/HeJ
  0 1 2 3 4 Mean P value 0 1 2 3 4 Mean P value 0 1 2 3 4 Mean P value
Steatosis                                          
 Con 10 1 0 0 0 0.09 0.0028 6 2 3 0 0 0.73 0.0020 10 0 0 0 0 0.00 0.0001
 HF 2 4 6 1 0 1.46 0 2 1 2 8 3.23 1 4 5 4 0 1.86
Fibrosis                                          
 Con 0 0 0 0 0 0.00 — 11 0 0 0 0 0.00 0.0885 10 0 0 0 0 0.00 —
 HF 0 0 0 0 0 0.00 10 3 0 0 0 0.23 14 0 0 0 0 0.00
Lobular inflammation                                          
 Con 11 0 0 0   0.00 0.0038 11 0 0 0   0.00 <0.0001 10 0 0 0   0.00 0.0641
 HF 6 7 0 0   0.54 1 12 0 0   0.92 10 4 0 0   0.29
Portal inflammation                                          
 Con 11 0 0 0   0.00 0.0885 11 0 0 0   0.00 0.0001 10 0 0 0   0.00 —
 HF 10 3 0 0   0.23 3 10 0 0   0.77 14 0 0 0   0.00
Balloon degeneration                                          
 Con 0 0 0     0.00 0.0062 11 0 0     0.00 <0.0001 10 0 0     0.00 <0.0001
 HF 5 7 1     0.69 0 0 13     2.00 1 3 10     1.64

Frequency of steatosis (0–4), lobular and portal inflammation (0–3), fibrosis (0–4), and balloon degeneration (0–2), along with mean scores and P values for control versus high fat diet within a given strain based on Chi-squared statistical analyses.