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ERα is abundantly expressed in adipose tissue of female mice and increases upon E2 administration. A: mRNA abundance of ERα vs. ERβ in adipose tissue of HF-fed female Ace2+/+ OVX mice. B: ERα mRNA abundance in adipose tissue from HF-fed OVX female mice of each genotype administered vehicle or E2. Data are means ± SE from n = 5–10 mice per group/genotype. *P < 0.05 vs. vehicle within genotype, **P < 0.01 vs. ERα (by two-tailed t-test).
