Table 1.
Control (Vehicle) | Ferristatin II (40 mg) | P Value | |
---|---|---|---|
Body weight, g | 69.2 ± 1.7 | 65.0 ± 0.8 | 0.0642 |
Hematocrit, % | 34.0 ± 2.3 | 32.1 ± 0.3 | 0.4457 |
Serum iron, μg/ml | 3.0 ± 0.4 | 0.9 ± 0.4 | 0.0093 |
Unsaturated iron binding capacity, μg/ml | 1.2 ± 0.2 | 2.8 ± 0.2 | 0.0016 |
Total iron binding capacity, μg/ml | 4.2 ± 0.3 | 3.7 ± 0.3 | 0.2576 |
Transferrin saturation, % | 71.2 ± 5.7 | 23.1 ± 8.1 | 0.0028 |
Liver nonheme iron, μg/g | 59.2 ± 7.6 | 91.3 ± 14.9 | 0.1036 |
Spleen nonheme iron, μg/g | 30.7 ± 4.5 | 64.8 ± 9.5 | 0.0176 |