Table 1.

Comparison of WIA metrics between PH patients and controls

Parameter	Patient	Control	P
PWV,‡ m/s
Right	1.26 (0.07)	0.73 (0.07)	4e−5
Left	1.46 (0.12)	0.70 (0.06)	1e−5
Mean	1.36 (0.08)	0.72 (0.05)	3e−7
Acceleration time,‡ ms
Right	60 (4)	108 (9)	0.0004
Left	74 (5)	135 (16)	0.005
Mean	67 (4)	121 (11)	0.001
FCW peak,† cm5/s
Right	0.09 (0.11)	0.18 (0.14)	0.03
Left	0.06 (0.06)	0.06 (0.08)	0.4
Mean	0.08 (0.08)	0.15 (0.11)	0.06
FCW peak time,‡ ms
Right	29 (2)	33 (3)	0.2
Left	33 (2)	42 (4)	0.05
Mean	31 (2)	38 (3)	0.03
FCW area,† cm5
Right	0.003 (0.004)	0.005 (0.005)	0.01
Left	0.002 (0.002)	0.003 (0.003)	0.02
Mean	0.002 (0.002)	0.005 (0.003)	0.006
BCW peak,† cm5/s
Right	0.01 (0.02)	0 (0)	6e−8
Left	0.006 (0.02)	0 (0)	6e−8
Mean	0.01 (0.01)	0 (0)	6e−8
BCW peak time,*‡ ms
Right	73 (6)	—	—
Left	79 (8)	—	—
Mean	76 (6)	—	—
BCW area,† cm5
Right	0.0004 (0.0005)	0 (0)	6e−8
Left	0.0003 (0.0006)	0 (0)	6e−8
Mean	0.0004 (0.0006)	0 (0)	6e−8
BEW peak,† cm5/s
Right	0 (0)	0.02 (0.02)	9e−6
Left	0 (0)	0.01 (0.01)	1e−6
Mean	0 (0)	0.01 (0.01)	1e−6
BEW peak time,*‡ ms
Right	—	30 (4)	—
Left	40 (2)	56 (7)	—
Mean	41 (2)	45 (5)	—
BEW area,† cm5
Right	0 (0)	0.0005 (0.0008)	9e−6
Left	0 (0)	0.0004 (0.0002)	3e−7
Mean	0 (0)	0.0005 (0.0005)	1e−7

WIA, wave intensity analysis; PH, pulmonary hypertension; PWV, pulse wave velocity; FCW, forward compression wave; BCW, backward compression wave; BEW, backward expansion wave.

^*Waveform absent in the majority of 1 group; therefore, statistical testing of timing parameters or ratios was not performed.

^†Nonnormally distributed, median (interquartile range), Mann-Whitney-U-test.

^‡Normally distributed, mean (SE), t-test ± Welch correction for unequal variances.