Table 1.
Subject characteristics
| Subject Characteristics | All Subjects | Nonasthmatic | Asthmatic | P Value |
|---|---|---|---|---|
| Number | 26 | 16 | 10 | — |
| Age, years | 31.8 ± 7.6 | 30.8 ± 6.9 | 33.5 ± 8.8 | 0.38 |
| Sex, female, N [%] | 13 [50] | 7 [44] | 6 [60] | 0.44 |
| Height, cm | 169 ± 10 | 167 ± 10 | 175 ± 8 | 0.06 |
| Body mass index, kg/m2 | 24.8 ± 5.0 | 24.0 ± 3.4 | 26.5 ± 7.3 | 0.28 |
| FEV1, l | 3.6 ± 0.9 | 3.7 ± 0.9 | 3.3 ± 0.7 | 0.23 |
| FEV1, % predicted | 97.5 ± 15.1 | 102.3 ± 15.5 | 89.9 ± 11.5 | 0.03* |
| FVC, l | 4.5 ± 1.1 | 4.5 ± 1.2 | 4.6 ± 1.0 | 0.85 |
| FVC, % predicted | 99.6 ± 13.7 | 101.8 ± 15.3 | 96.1 ± 10.4 | 0.30 |
| FEV1-to-FVC ratio | 0.79 ± 0.11 | 0.84 ± 0.06 | 0.69 ± 0.11 | 0.0006* |
| Atopy, % | 21 [81] | 11 [69] | 10 [100] | 0.05 |
| VE, l/min/m2 BSA | ||||
| With 0 ppb O3 | 21.7 ± 2.5 | 22.0 ± 2.7 | 21.2 ± 2.3 | 0.50 |
| With 100 ppb O3 | 21.9 ± 3.4 | 21.4 ± 3.2 | 22.9 ± 3.9 | 0.35 |
| With 200 ppb O3 | 21.9 ± 3.1 | 22.4 ± 2.6 | 20.8 ± 4.1 | 0.26 |
Values are means ± SD. FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; VE, average minute ventilation during exercise; BSA, body surface area; O3, ozone. P value is for comparison between asthmatic and nonasthmatic subjects by Student t-test.
*
Significant comparisons.