Table 5.

Systemic inflammation with ozone exposure

	0 ppb O3			100 ppb O3			200 ppb O3
Blood Inflammatory Indexes	0 h	4 h	24 h	0 h	4 h	24 h	0 h	4 h	24 h
Leukocytes, ×106 cells/ml	5.53 ± 1.23	8.69 ± 2.60	6.47 ± 1.74	5.93 ± 1.28	9.22 ± 2.16	6.45 ± 1.32	5.75 ± 1.25	8.95 ± 2.69	6.49 ± 1.36
Neutrophils, ×106 cells/ml	3.29 ± 1.10	6.09 ± 2.41	3.47 ± 1.32	3.60 ± 1.00	6.51 ± 1.83	3.48 ± 0.96	3.39 ± 0.95	6.41 ± 2.58	3.51 ± 1.21
Lymphocytes, ×106 cells/ml	1.59 ± 0.44	1.86 ± 0.47	2.21 ± 0.54	1.63 ± 0.49	1.95 ± 0.61	2.07 ± 0.59	1.68 ± 0.40	1.82 ± 0.54	2.17 ± 0.52
Monocytes, ×106 cells/ml	0.30 ± 0.08	0.41 ± 0.12	0.39 ± 0.15	0.34 ± 0.11	0.44 ± 0.14	0.38 ± 0.08	0.32 ± 0.11	0.41 ± 0.12	0.37 ± 0.13
Eosinophils, ×106 cells/ml	0.20 ± 0.15	0.18 ± 0.14	0.22 ± 0.14	0.21 ± 0.15	0.17 ± 0.12	0.24 ± 0.14	0.21 ± 0.14	0.15 ± 0.11	0.23 ± 0.16
CRP, mg/l	0.6 [0.4, 2.4]	0.6 [0.3, 2.5]	1.8 [0.7, 4.0]	0.6 [0.3, 2.8]	0.4 [0.2, 2.8]	2.5 [0.6, 6.1]	0.6 [0.3, 2.4]	0.7 [0.3, 2.4]	2.6 [1.2, 7.0]
ACE, U/l	37.5 [28.0, 50.0]	39.0 [32.5, 46.4]	38.8 [27.1, 49.1]	32.5 [26.5, 52.0]	35.2 [29.1, 53.9]	33.8 [28.1, 55.3]	37.5 [28.5, 50.0]	37.8 [29.8, 49.8]	38.5 [30.9, 48.9]
IL-6, pg/ml	1.7 [1.7, 1.7]	1.7 [1.7, 1.7]	1.7 [1.7, 1.7]	1.7 [1.7, 1.7]	1.7 [1.7, 1.7]	1.7 [1.7, 1.7]	1.7 [1.7, 1.7]	1.7 [1.7, 1.7]	1.7 [1.7, 1.7]
IL-8, pg/ml	6.0 [4.6, 12.0]	5.0 [4.6, 8.6]	6.6 [5.4, 8.8]	4.6 [4.6, 7.4]	4.8 [4.6, 8.4]	8.7 [4.6, 10.0]	4.6 [4.6, 7.6]	6.3 [4.6, 7.8]	6.5 [4.6, 10.4]

Values are means ± SD or median [interquartile range]. Concentrations of peripheral blood leukocytes, C-reactive protein (CRP), angiotensin-converting enzyme activity (ACE), IL-6, and IL-8 immediately before (0 h), immediately after (4 h), and 20 h after (24 h) ozone exposure are shown.