Fig. 4.

A folic acid-enriched diet protects against T+E2-induced increases in serum anti-diuretic hormone (ADH) concentration. Adult male mice were treated as described in Fig. 1. A and B: urine specific gravity was measured at 1 and 2 mo postsurgery; n ≥10/group. Other measurements included urine protein concentration (C), blood glucose concentration (D), serum anti-ADH concentration (E), and serum creatinine concentration (F) at 2 mo postsurgery. Values are means ± SE. *Significant difference, P ≤ 0.05; n ≥4/group.