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A folic acid-enriched diet and T+E2 induce lobe-specific changes in prostate and bladder global DNA methylation. Adult male mice were treated as described in Fig. 1. Percent global DNA methylation was measured in anterior (A), dorsal (B), lateral (C), and ventral prostate (D), and the bladder (E) at 14 wk of age. Values are means ± SE. *Significant difference, P ≤ 0.05; n = 5/group.
