Figure 4.

Masson’s Trichrome staining of granulation tissue in the wound area of all animal groups at the 15^th day after wounding in rats (G1) Skin dressed with vehicle shows more inflammatory cells; (G2) Skin dressed with Intrasite gel shows less inflammatory cells and more collagen produce compared to vehicle group; (G3) Skin dressed with 0.2 mL of P. macrocarpa 100 mg/mL; (G4) Skin dressed with 0.2 mL of P. macrocarpa 200 mg/mL show significantly decreased inflammatory cells and increase in the collagen production compared to vehicle (magnification 20x).