Table 2.
Frequency of reporting pulmonary toxicity, cardiac toxicity, or infectious complications (none vs. any) within 30 days of starting treatment by BMI status (normal: BMI<25.0; overweight: BMI 25.0–29.9; obese: BMI≥30.0)
| Toxicity
|
Overall
|
Normal
|
Overweight
|
Obese
|
p value | ||||
|---|---|---|---|---|---|---|---|---|---|
| Number | Percent | Number | Percent | Number | Percent | Number | Percent | ||
| Pulmonary | |||||||||
| None | 172 | 52.4% | 50 | 47.6% | 75 | 63.0% | 47 | 45.2% | 0.014 |
| Anya | 156 | 47.6% | 55 | 52.4% | 44 | 37.0% | 57 | 54.8% | |
| Cardiac | |||||||||
| None | 176 | 53.7% | 54 | 51.4% | 69 | 58.0% | 53 | 51.0% | 0.494 |
| Any | 152 | 46.3% | 51 | 48.6% | 50 | 42.0% | 51 | 49.0% | |
| Infection | |||||||||
| None | 119 | 36.3% | 41 | 39.0% | 43 | 36.1% | 35 | 33.7% | 0.719 |
| Any | 209 | 63.7% | 64 | 61.0% | 76 | 63.9% | 69 | 66.3% | |
p value based on chi-square analysis comparing toxicities (none vs. any) of patients with differing BMI categories
a
Patient who suffered mild, moderate, severe, life-threatening, or death within 30 days of starting treatment were categorized as having “any” toxicity