Table 2. Demographic and clinical characteristics of the cerebrospinal fluid samples.
| First sample | Second sample | |||||
|---|---|---|---|---|---|---|
| Control | Control | MDD | Control | Control | MDD | |
| N | 30 | 30 | 30 | 36 | ||
| Male/Female | 15/15 | 15/15 | n.s. | 15/15 | 16/20 | n.s. |
| Drug free | — | 10 | — | 4 | ||
| Age | 41.9 ± 14.3 (20–72) | 44.2 ± 12.3 (23–80) | n.s. | 40.7 ± 9.9 (22–58) | 43.3 ± 11.5 (22–76) | n.s. |
| Elapsed time from 10:00 (min) | 160.5 ± 124.4 (0–360) | 185.8 ± 104.3 (0–360) | n.s. | 202.9 ± 110.2 (0–355) | 218.7 ± 92.8 (0–390) | n.s. |
| HAM-D 17 | N/A | 16.5 ± 8.0 (0–31) | N/A | 13.4 ± 8.8 (1–39) | ||
| IMI-equivalent (mg/day) | N/A | 142 ± 135 (0–400) | N/A | 136.5 ± 147.9 (0–525) | ||
| CSF WCC (/mL) | 4.9 ± 3.7 (0–14) | 4.4 ± 2.7 (0–11) | n.s. | 3.5 ± 2.5 (0–10) | 3.1 ± 2.0 (0–8) | n.s. |
| CSF protein (mg/dL) | 38.0 ± 8.2 (24–59) | 43.9 ± 18.2 (21–107) | n.s. | 35.2 ± 8.7 (20–60) | 43.3 ± 18.1 (1–97) | n.s. |
MDD, major depressive disorder; HAM-D 17, 17-item version of Hamilton Depression Rating Scale; IMI, imipramine; WCC, white cell count. Values are mean ± standard deviation. Values in the parentheses indicate ranges.