Table 3.
Pharmacological procedure in new born and surgical procedure in 20-day-old rats | ||||||||
---|---|---|---|---|---|---|---|---|
Vehicle | Capsaicin | Vehicle | Capsaicin | Vehicle | Capsaicin | Vehicle | Capsaicin | |
SO | SO | SSON-L | SSON-L | SSON-R | SSON-R | SSON-B | SSON-B | |
LEFT OVARY | 3.8 ± 0.7 | 5.3 ± 0.9 | 0.9 ± 0.6ab | 3.2 ± 1.0 | 7.2 ± 0.6b | 4.1 ± 1.1e | 4.8 ± 1.4 | 3.8 ± 1.0 |
RIGHT OVARY | 5.8 ± 0.6a | 3.7 ± 0.5c | 6.5 ± 0.6 | 5.6 ± 0.9 | 2.5 ± 1.2ac | 2.7 ± 0.8c | 5.0 ± 1.4 | 2.5 ± 0.4c |
Pharmacological procedure in new born and surgical procedure in 28-day-old rats | ||||||||
Vehicle | Capsaicin | Vehicle | Capsaicin | Vehicle | Capsaicin | Vehicle | Capsaicin | |
SO | SO | SSON-L | SSON-L | SSON-R | SSON-R | SSON-B | SSON-B | |
LEFT OVARY | 3.1 ± 0.7 | 4.9 ± 1.1 | 2.3 ± 0.8a | 4.2 ± 0.7 | 5.2 ± 0.5 | 5.0 ± 1.1 | 3.0 ± 3.1 | 2.3 ± 0.7 |
RIGHT OVARY | 4.4 ± 0.8 | 4.5 ± 0.9 | 6.2 ± 0.8 | 4.8 ± 0.5 | 2.8 ± 0.7a | 2.0 ± 0.6 acd | 3.6. ± 1.1 | 3.5 ± 0.9 |
Mean ± SEM number of the ova shed in animals injected at birth with vehicle or capsaicin and subjected to SON sectioning. The rats were injected with vehicle or capsaicin at birth. At 20 or 28 days of age, the animals were subjected to a sham-operation (SO) or to left (L), right (R) or bilateral (B) SSON. All animals were sacrificed at the first vaginal estrus. Significance was noted as indicated. a p <0.05 VEHICLE + SO, VEHICLE + SSON-L or VEHICLE + SSON-R vs. the contralateral ovary of same group. b p <0.05 VEHICLE + SSON-L (left ovary) vs. VEHICLE + SO (left ovary). c p <0.05 VEHICLE + SSSON-R (right ovary) vs. VEHICLE + SO (right ovary). d p <0.05 CAPSAICIN + SSON-R (right ovary) vs. CAPSAICIN + SO (right ovary). e p <0.05 CAPSAICIN + SSON-R (left ovary) vs. VEHICLE + SSON-R (left ovary). Kruskal-Wallis test followed by the Mann–Whitney test