Table 2.
Baseline characteristics and IVF outcomes in the POA and control groups in women aged <33 years
| Characteristics | <33 years old | t/z(χ 2 ) | P | |
|---|---|---|---|---|
| Control | POA | |||
| n | 356 | 294 | ||
| Age(y)a | 28.64 ± 2.49 | 28.92 ± 2.37 | 1.462 | 0.144 |
| Infertility years(y)a | 3.84 ± 2.48 | 3.81 ± 2.34 | −0.140 | 0.889 |
| BMI(kg/m2)a | 21.30 ± 3.06 | 20.35 ± 2.27 | −4.528 | <0.001 |
| FSH(IU/L)a | 6.46 ± 1.03 | 9.21 ± 1.00 | 34.362 | <0.001 |
| LH(IU/L)b | 3.81(2.94–4.89) | 4. 78(3.62–5.82) | 44.850 | <0.001 |
| E2(ng/L)b | 38.00(25.90–51.00) | 37.77(26.00–50.58) | 0.039 | 0.844 |
| FSH/LHb | 1.76(1.32–2.18) | 1.95(1.57–2.50) | 20.869 | <0.001 |
| AFC(n)a | 16.14 ± 5.82 | 14.58 ± 5.25 | −3.554 | <0.001 |
| Total dose of Gn (IU)a | 1,874.20 ± 609.07 | 2,051.08 ± 612.17 | 3.639 | <0.001 |
| E2 level on DHCG (ng/L)b | 3,818.70 (2,413.24–4,800.00) | 3,563.50 (2,222.75–4,800.00) | 3.107 | 0.078 |
| Number of retrieved oocytes(n)a | 14.86 ± 7.35 | 12.55 ± 6.22 | −4.234 | <0.001 |
| Rate of POR(%)c | 1.42(5/353) | 6.46(19/294) | 11.585 | 0.001d |
| Number of frozen embryos (n)b | 5.00(3.00–8.00) | 5.00(3.00–8.00) | 3.895 | 0.048 |
| Number of available embryos (n)b | 7.00(5.00–10.00) | 7.00(4.00–9.00) | 3.761 | 0.052 |
| Fertilization rate(%)c | 84.62(66.67–94.44) | 85.71(71.43–100.00) | 1.858 | 0.173 |
| Cleavage rate(%)c | 100.00 (100.00–100.00) | 100.00 (100.00–100.00) | 0.221 | 0.638 |
| Cancellation rate(%)c | 0.84(3/356) | 2.72(8/294) | 3.415 | 0.065e |
| Pregnancy rate (%)c | 55.52(196/353) | 54.55(156/286) | 0.061 | 0.805 |
aThe normally distributed data are presented as the mean ± SD, including age, infertility years, BMI, FSH, AFC, total dose of Gn, and number of retrieved oocytes. The t-test was performed to analyze statistical significance
bThe non-normally distributed data are presented as the median (25–75th percentile). The non-parametric Mann–Whitney test was performed to calculate the Z-score
cThe chi-square (χ 2) test was performed to analyze statistical significance
dThe rate of POR = (the cycles of oocyte yields ≤ 3 + the cycles cancelled egg retrieval)/the total cycles
eThe cancellation rate only included the cycles of cancelled egg retrieval