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. 2015 Jun 18;16(1):465. doi: 10.1186/s12864-015-1651-9

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© Koskinen et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Genome-wide association study across four breeds and gene content of the associated locus on CFA37. a. Genome-wide association study including Belgian Shepherds, Schipperkes, Finnish Spitz, and Beagles highlights a single locus on CFA37. The SNPs showing the strongest association with IE are located in the ADAM23 gene. The red line indicates genome-wide significance level of p-values. b. The UCSC-based gene content of the 4.4 Mb critical region on CFA37, which was targeted and resequenced. The figure also includes the genotyped HD markers in the locus and annotation gaps in the CanFam3.1 reference