Table 1.

Haplotype analysis revealed a common risk haplotype for idiopathic epilepsy. A risk haplotype shared between the breeds was identified between 15085438 and 15113325 bp on CFA37. It consisted of alleles T-C-del-del-G-G at 15085438, 15106446, 15108593, 15108802, 15111724 and 15113325 bp in ADAM23

Breed	Risk haplo freq. cases	Risk haplo freq. controls	p-value	OR (95 % C.I.)	P-value (homozygosity)	OR (95 % C.I.) (homozygosity)	Cases/controls without risk haplotype
Belgian Shepherd	0.75	0.49	4.3e–11	3.2 (2.3–4.6)	4.1e–10	4.6 (2.8–7.6)	10 %/28 %
Schipperke	0.81	0.65	0.003	2.3 (1.3–4.0)	0.0006	3.3 (1.7–6.7)	6 %/9 %
Finnish Spitz	0.89	0.67	1.6e–05	4.1 (2.1–8.2)	4.9e–05	4.9 (2.2–10.8)	2 %/12 %
Beagle (Finnish hunting)	0.96	0.7	0.006	11.5 (1.4–93.1)	0.009	12 (1.4–106.2)	0 %/12 %
Beagle (German)	0.63	0.65	0.9	0.9 (0.3–2.6)	0.9	1.1 (0.3–4.6)	19 %/13 %

haplo freq haplotype frequency, OR odds ratio, C.I. confidence interval