Table 1.

Pharmacokinetics parameters after intravenous administration of Cefquinome in cattle at the dose (1 mg/kg) body weight.

PK parameters	Mean	SD
AUC (μg.h/mL)	8.04	0.34
K10 (l/h)	0.67	0.03
K12 (1/h)	0.39	0.09
K21 (1/h)	0.69	0.24
T ½α (h)	0.48	0.09
T 1/2 β (h)	2.10	0.45
V1 (L/kg)	0.18	0.00
CL (L/h.kg)	0.12	0.00
Vss (L/kg)	0.28	0.02
MRT (h)	2.30	0.30
AUMC (μg.h2/Ml)	18.56	2.19

AUC, Area under the concentration-time curve; K₁₀, First order elimination rate constant; K₁₂, First order transfer rate constant describing distribution between central and peripheral compartment; K₂₁, First order transfer rate constant describing distribution between peripheral and central compartment; T 1/2α, Half-life of distribution; T 1/2β, Half-life of elimination; CL, Systemic clearance; Vss, Volume of distribution at steady state; MRT, Mean residence time; AUMC, Area under the first moment-time curve.