Table 3.
Incidence, clinical symptomatology and etiologies of postoperative hyponatremia in 344 consecutive patients who underwent transsphenoidal resection of a pituitary mass at the authors’ institution between January, 2006, and December, 2012.
| Incidence of Post-operative Hyponatremia (N (%)) | 62 (18.0) |
|---|---|
| Hyponatremia Severity (N (%)) | |
| Mild (131–134 mEq/L) | 32 (51.6) |
| Moderate (125–130 mEq/L) | 19 (30.6) |
| Severe (≤124 mEq/L) | 11 (17.7) |
| Clinical Symptoms (N (%)) | |
| None | 43 (69.4) |
| Nausea/Vomiting | 10 (16.1) |
| Headache | 4 (6.5) |
| Malaise | 3 (4.8) |
| Agitation | 1 (1.6) |
| Confusion | 1 (1.6) |
| Balance difficulty | 1 (1.6) |
| Abdominal pain | 1 (1.6) |
| Primary Etiology (N (%)) | |
| Syndrome of inappropriate ADH secretion (SIADH) | 44 (71) |
| Cerebral salt wasting (CSW) | 15 (24.2) |
| Desmopressin acetate overdose | 3 (4.8) |
| Secondary Etiology (N (%)) | |
| Hypoadrenal state | 4 (6.5) |
| Desmopressin acetate overdose | 3 (4.8) |
| Ischemic cardiomyopathy | 1 (1.6) |
| Excessive oral intake of hypotonic fluids | 1 (1.6) |