Table 4.
Autoantigens in NMO and autoimmune encephalitides as examples of other CNS autoimmune diseases.
| Autoantigen | Remarks | Reference |
|---|---|---|
| Neuromyelitis optica | ||
| AQP-4 | Antibodies in 73% of NMO patients | (229) |
| MOG | Antibodies in 7% of NMO-spectrum disorder patients | (238) |
| Autoimmune encephalitides to membrane antigens | ||
| NMDA-receptor | Antibodies in patients with limbic encephalitis, psychotic behavior | (289, 291) |
| AMPA-receptor | Antibodies in patients with limbic encephalitis | (289) |
| GABAA-receptor | Antibodies in patients with anti-GABA-A receptor encephalitis | (318) |
| GABAB-receptor | Antibodies in patients with limbic encephalitis | (289) |
| Gly-receptor | Antibodies in patients with limbic encephalitis, Stiff person syndrome | (289) |
| DPPX | Antibodies in patients with anti-DPPX-associated encephalitis | (319) |
| GluR5 | Antibodies in patients with anti-GluR5 encephalitis | (320) |
| VGKC-complex | Antibodies in patients with limbic encephalitis, faciobrachial dystonic seizures, Morvan’s syndrome, neuromyotonia | (289) |
| Autoimmune encephalitides to intracellular antigens | ||
| Hu | T cells and antibodies in patients with anti-Hu encephalitis | (321, 322) |
| Jo (323, 324), Ri (325), Ma1 (326), Ma2 (327), Zic4 (328), GAD-65 (329), CRMP5 (330), and amphiphysin (331) as target of autoantibodies in patients with the respective encephalitis forms | ||