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An oligomerization-defective mutation in Fob1 promotes transcription-induced recombination at an ectopic Fob1-binding site located in the His3 ORF (HOT1 recombination). (A) Schematic representation of the recombination process showing the elimination of the Ade5 marker that produces red–white sectoring. (B) Representative photographs showing sectoring and nonsectoring cells. (C) Quantification of the recombination frequency (plasmid sectoring).
