TABLE II.
Concentrations of Other Amino Acids in Central Auditory Regions of Control and Intense-Tone-Exposed Hamsters†
| Taurine | Glutamine | Arginine | Threonine | Serine | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Region | Control | Exposed | Control | Exposed | Control | Exposed | Control | Exposed | Control | Exposed |
| AVCN main (9,14) | 13.9 ± 1.0 | 12.7 ± 0.6 | 26.2 ± 1.8 | 25.6 ± 1.1 | 1.2 ± 0.1 | 1.2 ± 0.1 | 3.7 ± 0.1 | 4.1 ± 0.1 | 4.4 ± 0.5 | 3.8 ± 0.4 |
| AVCN dorsal (4,6) | 14.0 ± 1.4 | 13.5 ± 0.9 | 29.8 ± 2.9 | 27.5 ± 1.9 | 1.1 ± 0.1 | 1.2 ± 0.1 | 4.2 ± 0.4 | 4.4 ± 0.2 | 4.2 ± 0.3 | 3.3 ± 0.6 |
| AVCN subgr (4,6) | 17.2 ± 1.4 | 15.0 ± 1.0 | 30.2 ± 1.8 | 28.5 ± 1.3 | 1.3 ± 0.1 | 1.4 ± 0.2 | 4.6 ± 0.3 | 4.5 ± 0.1 | 4.0 ± 0.6 | 4.1 ± 0.6 |
| AVCN gran (6,11) | 27.8 ± 1.8 | 25.0 ± 1.4 | 38.0 ± 1.6 | 37.0 ± 1.6 | 1.7 ± 0.2 | 2.0 ± 0.2 | 6.0 ± 0.4 | 6.7 ± 0.5 | 5.4 ± 0.9 | 6.2 ± 0.5 |
| PVCN caudal (13,15) | 17.0 ± 0.8* | 14.8 ± 0.6 | 25.9 ± 1.0 | 26.6 ± 0.8 | 1.7 ± 0.1 | 1.6 ± 0.1 | 4.7 ± 0.2 | 4.9 ± 0.2 | 4.6 ± 0.1* | 4.2 ± 0.1 |
| PVCN gran (3,4) | 31.6 ± 1.7* | 22.3 ± 2.5 | 34.5 ± 2.6 | 30.6 ± 1.7 | 1.7 ± 0.3 | 1.4 ± 0.2 | 7.0 ± 0.3* | 6.0 ± 0.2 | 6.3 ± 0.8 | 4.8 ± 0.3 |
| DCN deep (11,12) | 16.3 ± 0.8 | 14.6 ± 0.6 | 24.9 ± 1.0 | 25.0 ± 0.9 | 1.6 ± 0.1 | 1.5 ± 0.1 | 5.0 ± 0.2 | 5.0 ± 0.2 | 4.1 ± 0.3 | 3.7 ± 0.1 |
| DCN fus (11,12) | 22.2 ± 1.0 | 19.5 ± 0.8 | 31.0 ± 0.9 | 30.0 ± 0.7 | 1.6 ± 0.1 | 1.4 ± 0.1 | 6.2 ± 0.3 | 6.0 ± 0.2 | 4.8 ± 0.3 | 4.0 ± 0.3 |
| DCN mol (11,12) | 33.8 ± 0.8 | 32.3 ± 1.5 | 40.2 ± 1.4 | 40.0 ± 1.1 | 1.4 ± 0.1 | 1.5 ± 0.1 | 6.8 ± 0.3 | 6.7 ± 0.2 | 6.0 ± 0.4 | 5.7 ± 0.3 |
| Trapezoid body (4,5) | 8.9 ± 0.7 | 8.2 ± 0.6 | 10.4 ± 1.0 | 10.2 ± 0.5 | 1.3 ± 0.2 | 1.5 ± 0.2 | 2.0 ± 0.1 | 2.1 ± 0.3 | 2.2 ± 0.5 | 3.1 ± 0.3 |
| IC dorsal (18,18) | 14.0 ± 0.5* | 12.3 ± 0.4 | 29.4 ± 1.2 | 30.0 ± 1.3 | 1.0 ± 0.03 | 1.0 ± 0.03 | 8.4 ± 0.5 | 8.3 ± 0.5 | 2.1 ± 0.1 | 2.1 ± 0.1 |
| IC ventral (24,24) | 11.5 ± 0.2* | 10.8 ± 0.2 | 21.0 ± 0.5 | 21.6 ± 0.6 | 1.1 ± 0.02 | 1.1 ± 0.04 | 4.8 ± 0.2 | 4.8 ± 0.2 | 1.8 ± 0.04 | 1.8 ± 0.05 |
| IC lateral (16,17) | 14.2 ± 0.3 | 13.4 ± 0.5 | 25.1 ± 1.0 | 25.8 ± 1.0 | 1.1 ± 0.1 | 1.1 ± 0.02 | 6.6 ± 0.4 | 6.6 ± 0.4 | 2.3 ± 0.1 | 2.3 ± 0.1 |
| IC medial (6,6) | 18.8 ± 0.7 | 17.3 ± 1.2 | 40.9 ± 2.5 | 39.3 ± 1.7 | 1.0 ± 0.05 | 1.0 ± 0.04 | 12.4 ± 0.8 | 11.8 ± 0.8 | 2.8 ± 0.2 | 2.8 ± 0.1 |
| MG dorsal (15,18) | 17.1 ± 0.8 | 15.2 ± 0.8 | 38.1 ± 0.8 | 38.1 ± 1.1 | 0.8 ± 0.03 | 0.8 ± 0.02 | 7.9 ± 0.4 | 8.0 ± 0.3 | 3.2 ± 0.1 | 3.3 ± 0.2 |
| MG ventral (20,24) | 14.5 ± 0.3*** | 12.7 ± 0.3 | 35.7 ± 1.0 | 34.3 ± 1.0 | 0.8 ± 0.03 | 0.8 ± 0.03 | 6.7 ± 0.3 | 6.7 ± 0.2 | 3.0 ± 0.1 | 3.0 ± 0.1 |
| MG medial (5,6) | 12.2 ± 0.5 | 11.7 ± 0.3 | 28.4 ± 1.2 | 27.5 ± 1.6 | 0.9 ± 0.1* | 1.1 ± 0.1 | 5.7 ± 0.4 | 5.8 ± 0.1 | 3.3 ± 0.7 | 2.7 ± 0.1 |
| AC layer I (10,12) | 37.3 ± 1.4 | 36.3 ± 1.0 | 48.1 ± 1.4 | 50.4 ± 1.7 | 0.9 ± 0.1 | 1.0 ± 0.1 | 13.7 ± 0.7 | 14.1± 0.7 | 6.6 ± 0.3 | 6.0 ± 0.7 |
| AC layer II (10,12) | 35.9 ± 1.2 | 34.6 ± 1.6 | 47.7 ± 1.6 | 49.9 ± 2.2 | 1.0 ± 0.1 | 0.9 ± 0.1 | 14.2 ± 0.7 | 14.8 ± 0.9 | 6.9 ± 0.5 | 6.3 ± 0.6 |
| AC layer III (11,13) | 33.2 ± 0.9 | 31.7 ± 1.3 | 45.6 ± 1.3 | 46.1 ± 2.0 | 0.8 ± 0.1 | 1.0 ± 0.1 | 13.1 ± 1.4 | 12.9 ± 0.9 | 6.0 ± 0.3 | 5.7 ± 0.6 |
| AC layer IV (10,12) | 32.1 ± 1.5 | 30.7 ± 1.1 | 44.1 ± 2.0 | 45.9 ± 2.0 | 0.9 ± 0.1 | 0.9 ± 0.1 | 13.3 ± 1.8 | 12.9 ± 0.9 | 5.5 ± 0.7 | 5.9 ± 0.7 |
| AC layer V (11,12) | 29.2 ± 1.5 | 27.5 ± 1.1 | 43.6 ± 1.6 | 45.7 ± 2.1 | 0.5 ± 0.1 | 0.7 ± 0.05 | 10.9 ± 0.7 | 11.7 ± 0.7 | 5.2 ± 0.3 | 5.1 ± 0.4 |
| AC layer VI (11,15) | 28.6 ± 1.4 | 26.1 ± 0.7 | 42.7 ± 1.6 | 43.1 ± 1.5 | 0.7 ± 0.1 | 0.8 ± 0.04 | 10.8 ± 0.6 | 10.8 ± 0.5 | 5.5 ± 0.3 | 5.1 ± 0.3 |
| Ext capsule (5,5) | 22.1 ± 1.2 | 22.2 ± 1.3 | 19.1 ± 0.8 | 21.4 ± 2.2 | 1.1 ± 0.1 | 1.2 ± 0.1 | 5.7 ± 0.4 | 6.5 ± 0.6 | 4.9 ± 0.3 | 4.5 ± 0.5 |
†
Data presentation, numbers of hamsters represented, abbreviations, and numbers of samples assayed as in Table I. Cases with less than the full number of samples are: AVCN gran, eight for serine for exposed; MG ventral, 19 for all except taurine for control and 23 for all except taurine and glutamine for exposed; AC layer II, 11 for serine for exposed; AC layer III, 12 for serine for exposed; AC layer IV, nine for all except taurine for control and 11 for arginine and threonine and 10 for serine for exposed.
*
P < 0.05 control vs. exposed.
***
P < 0.001 control vs. exposed.