DHA‐P versus Artemether plus amodiaquine |
Trial ID |
Sample Size |
Blinding |
Clinical symptoms monitoring |
Biochemistry |
Haematological |
ECG |
Hasugian 2007 IDN |
334 |
Open label |
Clinical assessment daily until afebrile then weekly until day 42. |
None |
None |
None |
Karema 2006 RWA |
504 |
Open label |
Clinical assessment on days 0, 1, 2, 3, 7, 14, 21, and 28. |
Differential WBC count (and LFT at one site only) at days 0 and 14 |
None |
None |
Smithuis 2010 MMR |
316 |
Open label |
Review weekly for 9 weeks. |
None |
None |
None |
The 4ABC Study 2011 AF |
2477 |
Single blind |
Clinical assessment on days 1, 2, 3, 7, 14, 21, and 28. |
Liver and renal function tests at days 7 and 28 |
FBC at days 3, 7, 14, and 28 |
None |