Table 2.
Unadjusted associations between participant characteristics and correct recall of APOE genotype, number of risk-increasing alleles and lifetime risk estimate
| APOE genotype | Number of risk-increasing alleles | Lifetime risk estimate (± 5 percentage points) | Lifetime risk estimate (exact) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic | Correct | Incorrect | Unadj. sig. | Correct | Incorrect | Unadj. sig. | Correct | Incorrect | Unadj. sig. | Correct | Incorrect | Unadj. sig. |
| Overall | 182 (74.0 %) | 64 (26.0%) | N/A | 205 (83.3%) | 41 (16.7%) | N/A | 207 (84.1%) | 39 (15.9%) | N/A | 126 (51.2%) | 120 (48.8%) | N/A |
| Age | ||||||||||||
| Mean (SD) | 57.91 (13.09) | 59.62 (13.00) | p=0.37 | 57.24 (13.14) | 63.95 (11.21) | p=0.002 | 57.43 (13.00) | 63.26 (12.62) | p=0.010 | 56.46 (13.13) | 60.35 (12.73) | p=0.019 |
| Gender | ||||||||||||
| Female, N (%) | 95 (73.1%) | 35 (26.9%) | p=0.73 | 108 (83.1%) | 22 (16.9%) | p=0.91 | 109 (83.8%) | 21 (16.2%) | p=0.89 | 62 (47.7%) | 68 (52.3%) | p=0.24 |
| Male, N (%) | 87 (75.0%) | 29 (25.0%) | 97 (83.6%) | 19 (16.4%) | 98 (84.5%) | 18 (15.5%) | 64 (55.2%) | 52 (44.8%) | ||||
| Education, years of schooling | ||||||||||||
| Mean (SD) | 16.97 (2.24) | 16.14 (2.51) | p=0.01 | 17.13 (2.15) | 14.88 (2.33) | p<0.001 | 16.97 (2.21) | 15.62 (2.66) | p=0.001 | 16.78 (2.14) | 16.73 (2.53) | p=0.88 |
| Race | ||||||||||||
| African American, N (%) | 21 (58.3%) | 15 (41.7%) | 23 (63.9%) | 13 (36.1%) | 25 (69.4%) | 11 (30.6%) | 19 (52.8%) | 17 (47.2%) | ||||
| European-American, N (%) | 159 (77.2%) | 47 (22.8%) | p=0.03 | 178 (86.4%) | 28 (13.6%) | p=0.005 | 178 (86.4%) | 28 (13.6%) | p=0.047 | 105 (51.0%) | 101 (49.0%) | p=0.95 |
| Other, N (%) | 2 (50.0%) | 2 (50.0%) | 4 (100.0%) | 0 (0.0%) | 4 (100%) | 0 (0%) | 2 (50.0%) | 2 (50.0%) | ||||
| Family history (total number of relatives with Alzheimer's) | ||||||||||||
| Mean (SD) | 2.1 (1.9) | 1.6 (1.2) | p=0.025 | 2.1 (1.6) | 1.4 (1.2) | p=0.006 | 2.0 (1.5) | 1.9 (2.0) | p=0.80 | 2.1 (1.6) | 1.9 (1.6) | p=0.37 |
| Numeracy | ||||||||||||
| High, N (%) | 120 (80.0%) | 30 (20.0%) | p=0.012 | 136 (90.7%) | 14 (9.3%) | p<0.001 | 133 (88.7%) | 17 (11.3%) | p=0.03 | 83 (55.3%) | 67 (44.7%) | p=0.12 |
| Low, N (%) | 61 (65.6%) | 32 (34.4%) | 66 (71.0%) | 27 (29.0%) | 73 (78.5%) | 20 (21.5%) | 42 (45.2%) | 51 (54.8%) | ||||
| Self-reported comfort with numbers | ||||||||||||
| Mean (SD) | 4.72 (0.92) | 4.28 (1.11) | p=0.002 | 4.74 (0.96) | 3.96 (0.88) | p<0.001 | 4.66 (0.97) | 4.30 (1.07) | p=0.042 | 4.70 (0.98) | 4.51 (1.00) | p=0.14 |
| Anxiety | ||||||||||||
| Mean (SD) | 3.18 (4.03) | 4.05 (4.92) | p=0.17 | 3.27 (4.16) | 4.08 (4.85) | p=0.28 | 3.24 (3.87) | 4.31 (6.11) | p=0.32 | 3.11 (3.98) | 3.70 (4.56) | p=0.29 |
| Distress | ||||||||||||
| Mean (SD) | 4.21 (7.40) | 2.95 (6.51) | p=0.24 | 3.95 (7.46) | 3.65 (5.64) | p=0.82 | 3.76 (6.57) | 4.76 (10.32) | p=0.59 | 3.83 (7.01) | 3.97 (7.43) | p=0.88 |